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Inhaled medicinal nitrous oxide/oxygen mixture can be used in any situation that requires analgesia/sedation with a fast onset and offset, including emergency care. The low solubility of nitrous oxide in biological tissue and fluid means that medicinal nitrous oxide/oxygen mixture results in rapid pain relief and elimination of the gas from the lungs. A further safety feature is the composition of an inhaled mixture of 50% nitrous oxide and oxygen to prevent hypoxia during administration.
ENTONOX® is administered by inhalation, so there is no need to insert a cannula or set up an intravenous line. This means that this form of analgesia/sedation does not need to be administered by specialist anaesthetist, but can be administered by trained staff including paramedics.