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The low solubility of nitrous oxide in biological tissue and fluid means, in clinical practice, that medicinal nitrous oxide/oxygen mixture provide rapid pain relief and elimination of the gas from the lungs. A further safety feature is the composition of an inhaled mixture product consisting in a mixture of 50% nitrous oxide and oxygen to prevent hypoxia during administration.
ENTONOX® can be administered by inhalation through face or nose masks or mouthpieces. Because ENTONOX is administered by inhalation and therefore non-invasive, there is no need to insert a cannula or set up an intravenous line. This means that analgesia/sedation does not need to be administered by a specialist anaesthetist but can be administered by trained staff such as paramedics and nurses.